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Michele Colaci "Etiopathogenesis of Systemic Sclerosis: role of human Parvovirus B19"

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ISBN
9783659389733
Автор
Michele Colaci
Язык
английский
Год издания
2013
Количество страниц
96 шт.
Аннотация
Systemic sclerosis, one of the most obscure rheumatic autoimmune diseases, is characterized by endothelial dysfunction and activation of fibroblasts, leading to diffuse microangiopathy and fibrosis of skin and visceral organs. Parvovirus B19,the virus responsable of the Fifth Disease, may infect also endothalial cells and their bone marrow precursors, along with fibroblasts; moreover, it has been associated to several autoimmune disorders, among which also systemic sclerosis. Is there a role for the virus in the etiopathogenesis of systemic sclerosis?
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ISBN
9783659389733
Автор
Michele Colaci
Язык
английский
Год издания
2013
Количество страниц
96 шт.
Аннотация
Systemic sclerosis, one of the most obscure rheumatic autoimmune diseases, is characterized by endothelial dysfunction and activation of fibroblasts, leading to diffuse microangiopathy and fibrosis of skin and visceral organs. Parvovirus B19,the virus responsable of the Fifth Disease, may infect also endothalial cells and their bone marrow precursors, along with fibroblasts; moreover, it has been associated to several autoimmune disorders, among which also systemic sclerosis. Is there a role for the virus in the etiopathogenesis of systemic sclerosis?
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